Supplementary Figure S4 from Comprehensive Single-Cell RNA Atlas of Human Laryngeal Normal, Preneoplastic, and Tumorigenic States

Supplementary Figure S4. (A) CNV scores of 21 epithelial cell subclusters in four different types of tissue samples. B cells and T cells from the VCP group were used as the reference. (B–E) Inferred chromosomal CNV landscapes distinguishing epithelial cell subclusters from the VCP (B), VCL (C), LSCC (D), and LSCCP (E) groups based on scRNA-seq data. B cells and T cells from the VCP group served as the reference. Chromosomal amplifications are shown in red and deletions in blue. (F) SCENIC analysis identifying transcription factors in epithelial cell subclusters; malignant subclusters are annotated in yellow. (G) Comparison plot result of epithelial cell subclusters outgoing and incoming signal strength among four different tissues.