Supplementary Figure 6 from Unraveling the Tumor Microenvironment and PD-L1 Expression across Tissue Types in High-Grade Serous Ovarian Cancer in the NeoPembrOV/GINECO Phase II Randomized Trial

Key Points

MAIN FINDING: The trial reveals distinct immune infiltration patterns based on PD-L1 status in ovarian cancer samples.
KEY EVIDENCE: Analysis shows significant differences in immune cell presence according to PD-L1 expression levels.
APPROACH: Tissue samples were evaluated for gene expression and protein levels in a randomized trial setting.
SIGNIFICANCE: Understanding immune dynamics in the tumor microenvironment may guide future therapies for ovarian cancer.

Randomized trial assesses immune infiltration and PD-L1 status in tubo-ovarian samples, implying key insights into tumor dynamics.

Supplementary Figure 6. Immune infiltration at the gene expression and protein levels according to PD-L1 status assessed on tubo-ovarian samples.

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Collet et al. (2025) studied this question.

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