Supplementary Figure 6 from Nivolumab and Relatlimab for the Treatment of Patients with Unresectable or Metastatic Mismatch Repair–Proficient Colorectal Cancer

Key Points

Nivolumab and relatlimab are evaluated for treatment in unresectable or metastatic colorectal cancer patients.
The study validates the functional relevance of Th and Treg proximity in the tumor microenvironment.
Functional assays and proximity analyses were conducted on immune cells from patient samples.
These findings could enhance understanding of immune interactions and inform future treatment strategies.

Supplementary figure validates Th and Treg proximity in patients with metastatic colorectal cancer, suggesting interaction importance.

Supplementary Figure 6. Validating the functional relevance of Th and Treg proximity.

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Christenson et al. (2025) studied this question.

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