Sexual Risk Behaviors Among Men Who Have Sex with Men (MSM) Using Pre-Exposure Prophylaxis (PrEP): A Systematic Review

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Systematic review investigates sexual risk behaviors in MSM using PrEP, showing implications for HIV prevention.

MAIN FINDING: Pre-exposure prophylaxis (PrEP) significantly reduces HIV transmission among MSM, despite risk compensation behaviors.
KEY EVIDENCE: Results indicate that while PrEP is effective, it is associated with decreased condom use and increased high-risk sexual activities.
APPROACH: The review analyzed 14 high-quality studies, including cohort and randomized controlled trials, focusing on MSM aged 15 and older.
SIGNIFICANCE: Integrating PrEP with education and supportive interventions could enhance HIV prevention efforts in MSM communities.

Mahraniy et al. (2025) studied this question.

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