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August 2, 2025Open Access

Phyling: phylogenetic inference from annotated genomes

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Authors

CTCheng-Hung TsaiUniversity of California, RiversideJSJason StajichUniversity of California, Riverside

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Implication

Phyling demonstrates faster phylogenomic reconstruction of species phylogenies using genomic data, indicating effective ortholog identification methods.

Key Points

  • MAIN FINDING: Phyling efficiently reconstructs phylogenies from annotated genomes with improved speed and accuracy.
  • KEY EVIDENCE: Benchmark tests show Phyling outperforms OrthoFinder in speed while maintaining similar accuracy levels.
  • APPROACH: The tool uses Hidden Markov Models to identify orthologous genes from genomic data for species tree construction.
  • SIGNIFICANCE: Phyling's user-friendly design and efficient memory use make it suitable for large phylogenetic analyses.

Cite This Study

Tsai et al. (2025) studied this question.

synapsesocial.com/papers/689a0c72e6551bb0af8d03f5https://doi.org/10.1101/2025.07.30.666921
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