Alpha Protein Kinase 3 Gene Therapy Restores Heart Function in Mouse and Human Models of Cardiomyopathy

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1Cardiomyopathy in α-Kinase 3 (ALPK3)–Deficient Mice2011 · 49 citations
2. 2Untying the knot: protein quality control in inherited cardiomyopathies2018 · 19 citations
3. 3α Protein Kinase 3 Is Essential for Neonatal and Adult Cardiac Function2025 · 5 citations
4. 4ALPK3-deficient cardiomyocytes generated from patient-derived induced pluripotent stem cells and mutant human embryonic stem cells display abnormal calcium handling and establish that ALPK3 deficiency underlies familial cardiomyopathy2016 · 69 citations
5. 5Alpha kinase 3 signaling at the M-band maintains sarcomere integrity and proteostasis in striated muscle2023 · 33 citations