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August 2, 2025Frontiers in MicrobiologyOpen Access

Epidemiological and biological characteristics of IncR plasmids as multihost antibiotic resistance carriers

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Authors

DZDuo ZhangSLShuang LiXZXindan Zhang

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Overview

This review examines IncR plasmids' roles in antibiotic resistance and inter-host transmission in various bacteria, suggesting implications for public health.

Key Points

  • IncR plasmids are significant carriers of antibiotic resistance found across multiple Gram-negative bacteria.
  • They facilitate the spread of resistance genes by co-integrating with other plasmids, increasing their host range.
  • IncR plasmids demonstrate high stability and retention within bacterial populations despite a low copy number.
  • The review highlights the need for further research on IncR plasmids to combat global dissemination and improve antimicrobial therapy.

Cite This Study

Zhang et al. (2025) studied this question.

synapsesocial.com/papers/689a0c72e6551bb0af8d0480https://doi.org/10.3389/fmicb.2025.1622352
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