Chronic activation of a key exercise signal transducer, CaMKII, drives skeletal muscle aging and sarcopenia

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1Exercise Increases Ca²⁺–Calmodulin‐Dependent Protein Kinase II Activity in Human Skeletal Muscle2003 · 181 citations
2. 2Calcium Ion in Skeletal Muscle: Its Crucial Role for Muscle Function, Plasticity, and Disease2000 · 1,007 citations
3. 3JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age2015 · 947 citations
4. 4Activity-dependent and -independent nuclear fluxes of HDAC4 mediated by different kinases in adult skeletal muscle2005 · 148 citations
5. 5Role of Ca²⁺/calmodulin-dependent kinases in skeletal muscle plasticity2005 · 234 citations