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August 3, 2025Open Access

Reframing infectious diseases and antimicrobial resistance through a One Health lens: A systems approach to understanding complexity

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Authors

YPYen PhamSJSonja JansonTWTeresa M. Wozniak

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Overview

Qualitative analysis explores factors influencing antimicrobial resistance in human health, suggesting a coordinated, multi-sectoral intervention is necessary.

Key Points

  • AMR represents a complex global health threat, with regions like northern Australia showing up to 50% of infections resistant to antibiotics.
  • Involving 35 stakeholders from diverse health sectors helped reveal interconnected factors driving AMR dynamics.
  • Causal loop diagram analysis identified key drivers like antibiotic use and broader structural determinants impacting AMR factors.
  • A shift to community-based, coordinated strategies is crucial for effectively combating AMR beyond traditional health interventions.

Cite This Study

Pham et al. (2025) studied this question.

synapsesocial.com/papers/689a0c7be6551bb0af8d05c1https://doi.org/10.1101/2025.08.01.25332650
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