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August 3, 2025Open Access

MACGA: Multi-scale Adaptive Convolution with Graph Attention for LncRNA–Disease Association Prediction

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Authors

XLXiulai LiXLXin LiWZWen Zhang

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Overview

Neural network framework predicts lncRNA-disease associations accurately, highlighting implications for precision medicine.

Key Points

  • MACGA improves lncRNA-disease prediction accuracy over existing methods.
  • The framework combines graph attention and adaptive convolution to capture complex relationships.
  • Five-fold cross-validation showed AUC=0.9463 and AUPR=0.4119, outperforming state-of-the-art models.
  • Results suggest potential for MACGA in drug repositioning through lncRNA-bridging strategies.

Cite This Study

Li et al. (2025) studied this question.

synapsesocial.com/papers/689a0c7be6551bb0af8d072dhttps://doi.org/10.1101/2025.07.14.664702
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