August 4, 2025

Overall Survival Following Radical Surgery and Postoperative Chemotherapy in Colorectal Cancer Patients Aged ≥70 Years: A Population-Based Retrospective Cohort Study

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Postoperative chemotherapy in elderly patients showed an increased mortality risk with an adjusted hazard ratio of 1.44.
Out of 2,142 patients analyzed, 44.2% received postoperative chemotherapy, primarily younger individuals.
Comorbidity and frailty significantly influenced overall survival, potentially more than chemotherapy.
The study underscores the importance of geriatric assessment for personalized treatment strategies in elderly CRC patients.

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Retrospective cohort study finds increased mortality risk with postoperative chemotherapy in patients aged ≥70, indicating the role of comorbidity and frailty.

Cite This Study

Mun et al. (2025) studied this question.

synapsesocial.com/papers/689a0f86e6551bb0af8d0a62 https://doi.org/10.21203/rs.3.rs-6884777/v1

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Implication

Retrospective cohort study finds increased mortality risk with postoperative chemotherapy in patients aged ≥70, indicating the role of comorbidity and frailty.

Overall Survival Following Radical Surgery and Postoperative Chemotherapy in Colorectal Cancer Patients Aged ≥70 Years: A Population-Based Retrospective Cohort Study

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Overall Survival Following Radical Surgery and Postoperative Chemotherapy in Colorectal Cancer Patients Aged ≥70 Years: A Population-Based Retrospective Cohort Study

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Cite This Study

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