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August 4, 2025

Real-World Evaluation of Treatment Response and Adherence in Bipolar Disorder: A Cross-Sectional Study from a Semi-Urban South Indian Tertiary Care Hospital

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Authors

KDKrishna Kumar DhakchinamoorthiPMPavithra Krishna MoorthyRARamanandha Mishra Annadurai

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Overview

Cross-sectional study shows treatment response and adherence in bipolar disorder patients, indicating improved outcomes with individual regimens.

Key Points

  • Standard pharmacological therapy significantly reduced manic and depressive symptoms in bipolar disorder.
  • Post-treatment, symptom severity scores declined with mean differences of 5.14 for mania and 3.15 for depression.
  • Medication adherence improved significantly after treatment, particularly among patients with mild symptoms.
  • Individualized treatment regimens, along with psychosocial support, enhance management of bipolar disorder cases.

Cite This Study

Dhakchinamoorthi et al. (2025) studied this question.

synapsesocial.com/papers/689a0f8de6551bb0af8d0d71https://doi.org/10.21203/rs.3.rs-7192695/v1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A Review of Bipolar Disorder Among Adults1999 · 96 citations
  2. 2Anhedonia is associated with a specific depression profile and poor antidepressant response2024 · 38 citations
  3. 3Bipolar disorder2012 · 241 citations
  4. 4Nonadherence in bipolar disorder patients: A 14-year retrospective study2020 · 12 citations
  5. 5Validation of the 17‐item Hamilton Depression Rating Scale definition of response for adults with major depressive disorder using equipercentile linking to Clinical Global Impression scale ratings: analysis of Pharmacogenomic Research Network Antidepressant Medication Pharmacogenomic Study (PGRN‐AMPS) data2016 · 96 citations