August 5, 2025Frontiers in MedicineOpen Access

Antibiotic treatment for 7 days versus 14 days in patients with uncomplicated bloodstream infections: a Systematic review and meta-analysis of randomized controlled trials and trial sequential analysis

View Full Paper

Ask AI

Bookmark

Authors

CZChangyun ZhaoZhejiang Hospital CCChangqin ChenZhejiang Hospital DLDifan LuFirst Affiliated Hospital Zhejiang University

Discussion

Member takes

Implication

Meta-analysis found no differences in mortality between 7-day and 14-day antibiotic treatments for bloodstream infections, suggesting a shorter regime may be preferable.

Key Points

The meta-analysis included four randomized controlled trials involving 4,794 patients with bloodstream infections.
There were no significant differences in all-cause mortality or 90-day mortality between 7-day and 14-day antibiotic regimens.
The 7-day antibiotic regimen resulted in a shorter length of stay in the hospital compared to the 14-day regimen.
Further large-scale randomized controlled trials are needed to validate the findings regarding antibiotic duration.

Cite This Study

Zhao et al. (2025) studied this question.

synapsesocial.com/papers/689a0f93e6551bb0af8d107c https://doi.org/10.3389/fmed.2025.1617328

View Full Paper

Ask AI

Bookmark

Implication

Meta-analysis found no differences in mortality between 7-day and 14-day antibiotic treatments for bloodstream infections, suggesting a shorter regime may be preferable.

Antibiotic treatment for 7 days versus 14 days in patients with uncomplicated bloodstream infections: a Systematic review and meta-analysis of randomized controlled trials and trial sequential analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

Antibiotic treatment for 7 days versus 14 days in patients with uncomplicated bloodstream infections: a Systematic review and meta-analysis of randomized controlled trials and trial sequential analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider