August 5, 2025

A Rare Case of Thymic Epithelial Tumor: AB-Type Thymoma coexisting with Thymic Adenocarcinoma and Review of literature

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This case presents an exceptional occurrence of AB-type thymoma coexisting with thymic adenocarcinoma in one mediastinal mass.
Pathological analysis confirmed distinct components with varying Ki67 proliferation indexes of 80% for thymoma and 30% for adenocarcinoma.
The patient, a 65-year-old female, successfully underwent resection and has remained disease-free for 4 months postoperatively.
The findings underline the need for careful diagnosis of tumor heterogeneity in mediastinal masses through immunohistochemical staining.

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Case report reveals rare thymic epithelial tumors in a 65-year-old female, highlighting tumor heterogeneity and diagnostic importance.

Pei et al. (2025) studied this question.

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