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August 5, 2025

Direct and indirect factors associated with health-related quality of life among PLHIV on second-line antiretroviral therapy at Dessie and Woldia Comprehensive Specialized Hospitals in Ethiopia: application of structural equation modelling

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Authors

KTKeleb Takele TirunehTTTesfaye Birhane TegegneFBFikade Demeke Bayou

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Overview

Cross-sectional study examines quality of life impacts from internalized stigma and support in PLHIV receiving second-line antiretroviral therapy.

Key Points

  • MAIN FINDING: Internalized stigma and depression negatively influence the quality of life for people living with HIV on therapy.
  • KEY EVIDENCE: Quality of life score averaged 48.7, with a notable negative association with internalized stigma (β̂ = -0.59).
  • APPROACH: Study used cross-sectional data from 825 participants, analyzed with structural equation modeling for insights.
  • SIGNIFICANCE: Highlights the need for mental health support in comprehensive HIV care to enhance quality of life.

Cite This Study

Tiruneh et al. (2025) studied this question.

synapsesocial.com/papers/689a0f99e6551bb0af8d13bahttps://doi.org/10.21203/rs.3.rs-6897343/v1
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