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August 5, 2025

The Relationship between Nonrestorative Sleep and Persistent Post-Acute Sequelae of COVID-19: A Longitudinal Study of Recovery Trajectories

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Authors

MHMegumi HazumiMKMayumi KataokaKUKentaro Usuda

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Overview

Longitudinal study shows nonrestorative sleep is linked to post-acute sequelae of COVID-19 persistence, suggesting distinct underlying mechanisms.

Key Points

  • Nonrestorative sleep significantly contributes to the persistence of post-acute sequelae of COVID-19, showing a relative risk of 1.33.
  • Among 957 initial participants, 559 completed follow-up assessments, providing robust data for analysis.
  • The study employed a one-year prospective cohort design, assessing sleep disturbances and PASC symptoms via an online survey.
  • Findings indicate the need to address nonrestorative sleep in patients recovering from COVID-19 for better recovery outcomes.

Cite This Study

Hazumi et al. (2025) studied this question.

synapsesocial.com/papers/689a0f99e6551bb0af8d1445https://doi.org/10.21203/rs.3.rs-7271333/v1
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