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August 5, 2025

From Silence to Diagnosis: Non-Invasive Detection of Liver Fibrosis in Adults with Inborn Errors of Immunity

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Authors

SDSusamber DikGÖGüzin ÖzdenUniversity of Health SciencesLÇLeyla ÇevirmeTrakya University

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Implication

This study evaluates liver fibrosis scoring systems in 41 adults with inborn errors of immunity, suggesting reliable non-invasive methods for early disease detection.

Key Points

  • Liver fibrosis is a significant complication in adults with inborn errors of immunity, requiring early identification.
  • Transient elastography accurately measures liver stiffness, correlating with liver enzyme levels in patients.
  • The study found AUC values of 0.647 for APRI, 0.665 for FIB-4, and 0.684 for NFS, indicating diagnostic performance.
  • Optimal cut-off values were established for APRI, FIB-4, and NFS, aiding in timely liver disease assessment.

Cite This Study

Dik et al. (2025) studied this question.

synapsesocial.com/papers/689a0f99e6551bb0af8d14a9https://doi.org/10.21203/rs.3.rs-7108234/v1
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Also Consider

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  1. 1Evaluation of hepatic injury in chronic hepatitis B and C using APRI and FIB-4 indices compared to fibroscan results2024 · 8 citations
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  4. 4Human inborn errors of immunity: 2024 update on the classification from the International Union of Immunological Societies Expert Committee2025 · 337 citations
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