August 6, 2025Frontiers in ImmunologyOpen Access

Associated factors in the development of rapidly progressive interstitial lung disease in patients with idiopathic inflammatory myopathies: a systematic review and meta-analysis

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Authors

WYWeiwei YuanNorthwest A&F University XZXuefei ZhouUniversity of Nottingham Ningbo China YYYahui YangFujian Normal University

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Implication

Meta-analysis identifies risk factors for rapidly progressive interstitial lung disease in patients with idiopathic inflammatory myopathy, suggesting targeted management strategies.

Key Points

Rapidly progressive interstitial lung disease is a severe complication in idiopathic inflammatory myopathy patients.
Significant risk factors include anti-MDA5 antibodies (OR = 6.044) and elevated C-reactive protein (OR = 3.366).
The study analyzed 21 retrospective studies involving 2,099 patients to identify these factors.
Findings provide insights for early diagnosis and management of interstitial lung disease in affected patients.

Cite This Study

Yuan et al. (2025) studied this question.

synapsesocial.com/papers/689a0fa0e6551bb0af8d16f0 https://doi.org/10.3389/fimmu.2025.1628928

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Implication

Meta-analysis identifies risk factors for rapidly progressive interstitial lung disease in patients with idiopathic inflammatory myopathy, suggesting targeted management strategies.

Associated factors in the development of rapidly progressive interstitial lung disease in patients with idiopathic inflammatory myopathies: a systematic review and meta-analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

Associated factors in the development of rapidly progressive interstitial lung disease in patients with idiopathic inflammatory myopathies: a systematic review and meta-analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

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