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August 6, 2025Journal of Affective DisordersOpen Access

The sleep-anxiety dysregulation model of alcohol use disorder risk: A nine-year longitudinal machine learning study

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Authors

NZNur Hani ZainalNDNatalia Van Doren

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Overview

Longitudinal study shows sleep disturbances predict alcohol use disorder in midlife adults, suggesting co-occurring anxiety's role.

Key Points

  • The study finds a significant link between sleep disturbances and nine-year alcohol use disorder (AUD) risk.
  • A longitudinal analysis of 1054 adults shows lower rest-stage activity strongly predicts AUD symptoms over time.
  • Machine learning techniques identified key predictors like sleep fragmentation and anxiety severity for AUD outcomes.
  • The proposed Sleep-Anxiety Dysregulation Model indicates chronic arousal regulation issues contribute to AUD development.

Cite This Study

Zainal et al. (2025) studied this question.

synapsesocial.com/papers/689a0fa0e6551bb0af8d174ahttps://doi.org/10.1016/j.jad.2025.120035
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