OS analysis indicates ferroptosis levels predict treatment success in melanoma and urothelial cancers.
Ferroptosis is associated with favorable treatment outcomes in patients receiving immunotherapy. A, The flow chart shows the design of the study. B, OS analysis of patients based on ferroptosis levels in tumor tissue in the IMvigor210 cohort (urothelial cancers). C, OS analysis of patients based on ferroptosis levels in tumor tissue in the Snyder cohort (melanoma). D, OS analysis of patients based on ferroptosis levels in tumor tissue in the Liu cohort (melanoma). E, OS analysis of patients based on ferroptosis levels in tumor tissue in the Lauss cohort (melanoma). The log-rank test was applied for the survival analysis. GSEA, gene set enrichment analysis.
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Zhou et al. (2025) studied this question.
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