OS analysis shows ferroptosis predicts outcomes in cancer patients with liver metastasis, implying its relevance in immunotherapy.
Ferroptosis complements liver metastasis and TMB to predict immunotherapy outcomes. A, OS analysis of patients based on the status of liver metastasis and ferroptosis in tumor tissue in the IMvigor210 cohort. B, OS analysis of patients based on the status of liver metastasis and ferroptosis in tumor tissue in the Liu cohort. C, OS analysis of patients based on TMB and ferroptosis in tumor tissue in the IMvigor210 cohort. D, OS analysis of patients based on TMB and ferroptosis in tumor tissue in the Liu cohort. The log-rank test was applied for the survival analysis.
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Zhou et al. (2025) studied this question.
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