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August 6, 2025

Supplementary Fig. S6 from Evaluation of Ferroptosis as a Biomarker to Predict Treatment Outcomes of Cancer Immunotherapy

Zhijun Zhou Yang Cai Hao Yuan Qun Chen Sophia W. Zhao Jingxuan Yang Mingyang Liu Alex X. Arreola Yu Ren Chao Xu Lacey R. McNally Michael S. Bronze Courtney W. Houchen Kuirong Jiang Wei R. Chen Yuqing Zhang Min Li

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Key Points

MAIN FINDING: Ferroptosis may serve as a relevant biomarker for predicting treatment outcomes in cancer immunotherapy.
KEY EVIDENCE: A correlation was found between tumor mutation burden (TMB) and ferroptosis in patients receiving immunotherapy.
APPROACH: The study utilized patient data to analyze the relationship between TMB and ferroptosis levels.
SIGNIFICANCE: These insights could help optimize immunotherapy strategies by identifying responsive patients based on ferroptosis.

Implication

Correlation between TMB and ferroptosis in patients receiving immunotherapy suggests new predictive insights.

Abstract

Supplementary Fig. S6. Correlation between TMB and ferroptosis in patients received immunotherapy.

Discussion

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Cite This Study

Zhou et al. (2025) studied this question.

synapsesocial.com/papers/689a0fa0e6551bb0af8d19da https://doi.org/10.1158/2767-9764.29836651

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Supplementary Fig. S3 from Evaluation of Ferroptosis as a Biomarker to Predict Treatment Outcomes of Cancer Immunotherapy2025
2Supplementary Fig. S5 from Evaluation of Ferroptosis as a Biomarker to Predict Treatment Outcomes of Cancer Immunotherapy2025
3Supplementary Fig. S4 from Evaluation of Ferroptosis as a Biomarker to Predict Treatment Outcomes of Cancer Immunotherapy2025
4Supplementary Fig. S2 from Evaluation of Ferroptosis as a Biomarker to Predict Treatment Outcomes of Cancer Immunotherapy2025
5Figure 2 from Evaluation of Ferroptosis as a Biomarker to Predict Treatment Outcomes of Cancer Immunotherapy2025

Supplementary Fig. S1 from Evaluation of Ferroptosis as a Biomarker to Predict Treatment Outcomes of Cancer Immunotherapy2025
Figure 1 from Evaluation of Ferroptosis as a Biomarker to Predict Treatment Outcomes of Cancer Immunotherapy2025
Figure 3 from Evaluation of Ferroptosis as a Biomarker to Predict Treatment Outcomes of Cancer Immunotherapy2025