The influence of morphofunctional asymmetries on the hormonal status of perimenopausal migrant women who lived in the zone of military conflict for a long time

The study of adaptation status in menopausal women who have lived in war zones for a long time is of special scientific interest due to the stress vulnerability of this category of migrants caused by neurovegetative, psychoemotional, endocrine and metabolic changes that develop against the background of reduced ovarian hormonal function. Morphofunctional asymmetries (lateral phenotype) are an important constitutional trait mediating the character of adaptability and non-specific resistance. The aim of the study was to examine patterns of adaptation in perimenopausal refugee women, taking into account their lateral phenotype. The study involved 154 women from the DNR and LNR and 142 women from Rostov Oblast. The Annett test (to determine the lateral profile) was used. Hormone levels were measured by immunoenzyme analysis. The results of these studies showed significantly higher levels of gonadotropic and corticotropic hormones (FSH, LH, and ACTH) with a significantly more pronounced decrease in melatonin levels in women with ambidextrous lateral phenotype, predominantly in residents of the DNR and LNR against the background of chronic stress.