Editorial highlights standardized diagnosis and treatment for infectious corneal epitheliopathy, suggesting improved visual outcomes through comprehensive methods.
By summarizing the diverse pathogens (viruses, bacteria, fungi, amoebae) and clinical features of infectious corneal epitheliopathy, this editorial clarifies the key points in diagnosis and differential diagnosis. Emphasizing the golden window of epithelial-stage intervention, it advocates a comprehensive diagnostic approach integrating medical history, slit-lamp findings, microbiological tests (corneal scraping, special staining/culture), in vivo confocal microscopy, and molecular diagnostics (tear virus antibodies, metagenomic sequencing). The tripartite evidence chain of "history-imaging-pathogen" is proposed to transcend morphology-dependent empiricism, with strict caution against glucocorticoid use before etiological confirmation. Standardized precision diagnosis at the epithelial stage is pivotal for early intervention and visual prognosis improvement.
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Xu et al. (2025) studied this question.
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