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August 7, 2025Proceedings of the National Academy of SciencesOpen Access

Tracing SARS-CoV-2 clusters across local scales using genomic data

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Authors

LLLeke LyuUniversity of GeorgiaMGMandev S. GillUniversity of GeorgiaGSGuppy StottUniversity of Georgia

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Overview

Quantitative analysis traced transmission dynamics in Greater Houston, indicating key local outbreaks and cluster patterns.

Key Points

  • Over 26,000 sars-cov-2 genomes analyzed revealed more than 1,000 independent introduction events.
  • Majority of viral introductions were domestic, while earlier international sources led to larger clusters.
  • Age-structured transmission dynamics were observed within locally circulating clusters.
  • Geographic analysis identified Harris County as a crucial viral source, supporting targeted public health strategies.

Cite This Study

Lyu et al. (2025) studied this question.

synapsesocial.com/papers/689dfe90d61984b91e13bd3dhttps://doi.org/10.1073/pnas.2501435122
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