Multiple Verrucous Nodules and Masses in an Adolescent Boy With Porokeratoma: A Case Report and Literature Review.

Very few cases of porokeratoma have been reported in the literature. We report a 14-year-old boy with porokeratoma presenting with multiple verrucous nodules and masses. Histopathology revealed significant hyperkeratosis of the epidermis, acanthosis, papillomatosis, hypogranulosis, and the epidermis formed large depressions filled with prominent broad cornoid lamellae. After excision of larger nodules, the patient was treated for 3 months with oral acitretin and topical retinoic acid, after which some nodules and masses subsided. Limitations include the unavailability of HPV virology and molecular genetic profiling, which would have been helpful, if not essential.