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August 8, 2025Frontiers in ImmunologyOpen Access

Identification of cellular factors associated with inflammation and neurodegeneration in multiple sclerosis

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Authors

ARAlexander Rodero-RomeroJFJosé Ignacio Fernández-VelascoEMEnric Monreal

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Overview

Cross-sectional study identifies inflammatory profiles and cellular factors in multiple sclerosis patients, implying distinct disease courses.

Key Points

  • Increased inflammatory T and B cells were found in all multiple sclerosis patients.
  • The NH group showed lower regulatory cell frequencies compared to healthy controls, indicating heightened inflammation.
  • Flow cytometry was used to analyze cytokine production in T and B cells from blood and cerebrospinal fluid samples.
  • The research highlights distinct inflammatory profiles among multiple sclerosis patients that could influence treatment strategies.

Cite This Study

Rodero-Romero et al. (2025) studied this question.

synapsesocial.com/papers/689dfea6d61984b91e13c855https://doi.org/10.3389/fimmu.2025.1648725
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