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Randomized controlled trial reveals digital therapy improves fatigue and distress symptoms in cancer patients, suggesting benefits for psycho-oncological care.
In this randomized controlled trial, we investigated the efficacy of the digital cognitive behavioral therapy-based program lancivis in improving quality of life (QoL), cancer-related fatigue, distress symptoms and fear of cancer progression in N = 604 cancer patients and survivors in Germany. Participants in the intervention group (IG; n = 304) used lancivis alongside treatment as usual (TAU) while participants in the control group (CG; n = 300) received TAU only. Intent-to-treat (ITT) analyses revealed significant improvements in fatigue in the IG compared to the CG after 3 months (T1; Cohen's d: 0.29) and 6 months (T2; Cohen's d: 0.31). Participants in the IG reported also significantly lower fear of cancer progression than the CG at T1 and T2 and lower levels of distress symptoms at T2. No between group differences were found for health-related QoL. Results suggest that lancivis may present a beneficial addition to psycho-oncological care services.
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Betz et al. (2025) studied this question.
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