August 13, 2025

Dual Route Amine Functionalized Poly(l-lactic acid)/Mesoporous Bioactive Glass Based 3D Printed Composite Scaffolds: An Investigation on In Vitro and In Vivo Characteristics.

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Dual route modification of mesoporous bioactive glass enhances mechanical strength of scaffolds by about 144%.
Hydroxyapatite formation occurs rapidly within 1 day when using modified scaffolds in simulated body fluids.
In vitro studies show PLA/N-MBG/PEI scaffolds have superior biocompatibility and osteogenic activity at 14 days.
In vivo experiments in Wistar rats reveal effective bone regeneration without chronic inflammation, solidifying their potential in tissue engineering.

Authors

SPShubham PantCentral Electrochemical Research Institute ANAvinash Chaitanya Sagar NakkaMissouri College JDJ. DevarathnamMissouri College

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Implication

In vitro and in vivo tests demonstrate enhanced osteogenic activity and biocompatibility in 3D printed scaffolds, suggesting improvements in bone tissue engineering.

Cite This Study

Pant et al. (2025) studied this question.

synapsesocial.com/papers/689e03efd61984b91e13d5cd https://doi.org/10.1021/acsabm.5c00813

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Implication

In vitro and in vivo tests demonstrate enhanced osteogenic activity and biocompatibility in 3D printed scaffolds, suggesting improvements in bone tissue engineering.

Dual Route Amine Functionalized Poly(l-lactic acid)/Mesoporous Bioactive Glass Based 3D Printed Composite Scaffolds: An Investigation on In Vitro and In Vivo Characteristics.

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Discussion

Implication

Cite This Study

Dual Route Amine Functionalized Poly(l-lactic acid)/Mesoporous Bioactive Glass Based 3D Printed Composite Scaffolds: An Investigation on In Vitro and In Vivo Characteristics.

Key Points

Discussion

Implication

Cite This Study

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