Fibrin Glue-Assisted Repair in Recurrent Retinal Detachment Following Post-Viral Retinitis: A Retrospective Analysis of 12 Cases in HIV-Positive Patients.

To evaluate the anatomical and functional outcomes of fibrin glue application in the surgical management of recurrent rhegmatogenous retinal detachment (RRD) in patients with healed post-viral retinitis and HIV infection. A retrospective review was conducted of 40 cases of RRD secondary to viral retinitis in HIV-positive patients. Among these, 12 eyes exhibited recurrent detachment under silicone oil and were managed with silicone oil exchange, using fibrin glue to close persistent retinal breaks. Pre- and postoperative visual acuity, anatomical reattachment, and complications were assessed. The time to fibrin glue resorption and any evidence of epiretinal membrane formation were also recorded. All 12 cases achieved successful retinal reattachment post fibrin glue application. Silicone oil removal was performed between 3 to 4 months postoperatively. Best corrected visual acuity improved in all eyes (mean preoperative LogMAR VA 1.2 ± 0.13 improved to 0.53 ± 0.13, p < .001). There were no pre-operative or post-operative complications. Nineteen of the total 40 cases required concurrent cataract surgery. Fibrin glue is a safe and effective adjunct for managing persistent retinal breaks in recurrent RRD under silicone oil in HIV-positive individuals with resolved viral retinitis. It promotes retinal reattachment and improves visual outcomes with minimal complications.