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August 15, 2025

Top advances of the year: Bladder cancer.

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Authors

AAAndrea B. ApoloSASaad AtiqAKAndre R. Kydd

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Overview

Highlights five advances in bladder cancer treatment, implying improved outcomes for urothelial carcinoma patients.

Key Points

  • Novel drug-delivery mechanisms enhance intravesical therapy options for nonmuscle-invasive and muscle-invasive bladder cancer.
  • Immune checkpoint inhibition has doubled disease-free survival in patients with high-risk muscle-invasive bladder cancer.
  • Circulating tumor DNA is identified as a promising biomarker for choosing patients for adjuvant immune checkpoint inhibition therapy.
  • A combination therapy has established a new standard of care for first-line treatment of metastatic urothelial carcinoma.

Cite This Study

Apolo et al. (2025) studied this question.

synapsesocial.com/papers/689fc3ee735da01f534db986https://doi.org/10.1002/cncr.70020
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