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August 14, 2025

Predictive biomarkers for post-neonatal necrotizing enterocolitis intestinal stenosis: Role of JMJD3, CRP, and PCT.

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Authors

TQTao QinCRChristopher RaoYDY DENG

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Overview

Retrospective analysis identifies JMJD3, CRP, and PCT as key biomarkers for intestinal stenosis in neonates, suggesting effective diagnostic potential.

Key Points

  • Post-necrotizing enterocolitis intestinal stenosis occurs in neonates, complicating NEC diagnosis and treatment.
  • Low platelet counts and elevated JMJD3, CRP, and PCT levels are significant in children with post-NEC intestinal stenosis.
  • JMJD3 levels are positively correlated with CRP and PCT, indicating active involvement in disease progression.
  • Combined assessment of CRP, PCT, and JMJD3 shows high diagnostic efficiency with sensitivity of 86.67% and specificity of 86.42%.

Cite This Study

Qin et al. (2025) studied this question.

synapsesocial.com/papers/689fc6852abb084d53ed242chttps://doi.org/10.17305/bb.2025.12766
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