Chronic Latent Invasive Fungal Laryngeal Cartilage Necrosis With Bilateral Vocal Cord Fixation as the Initial Symptom.

Invasive fungal infections are a serious threat to immunocompromised individuals, with laryngeal involvement being rare and often presenting with atypical symptoms that complicate early diagnosis. The authors report a case of chronic invasive fungal laryngeal cartilage necrosis, initially manifesting as bilateral vocal cord fixation. Pathology suggested Mucorales infection. Postoperative recovery included resolution of both laryngeal and pulmonary issues after a total laryngectomy. There has been no recurrence at follow-up visits. Early diagnosis, aggressive surgical debridement, and full-course antifungal treatment are essential for improving outcomes in extrapulmonary fungal infections.