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August 11, 2025

From pre-pandemic to pandemic: Unravelling mental health trajectories in clinical and general population cohorts

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Authors

DCDiana CzepielMSMarit SijbrandijTHTrynke Hoekstra

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Overview

Observational analysis highlights symptom trajectories in general and clinical populations, indicating differing impacts of COVID-19.

Key Points

  • Most adults in the general population displayed stable or improving mental health symptoms during the pandemic, with about 80% showing decreases in anxiety and depression.
  • In the clinical population, approximately half demonstrated improvements in symptoms while the other half showed either high or low symptoms, highlighting variability in responses.
  • Data from six cohorts across Germany, France, and the Netherlands were analyzed using Latent Growth Mixture Modelling and logistic regressions to track symptom changes.
  • Findings suggest targeted mental health interventions are crucial, as not all individuals experienced negative outcomes during the pandemic.

Cite This Study

Czepiel et al. (2025) studied this question.

synapsesocial.com/papers/68a35ee30a429f7973327c78https://doi.org/10.31219/osf.io/zykhn_v1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Variation in symptoms of common mental disorders in the general population during the COVID-19 pandemic: longitudinal cohort study2024 · 4 citations
  2. 2Trajectories of depressive and anxiety symptoms and associated risk factors during the COVID-19 pandemic in Germany: A longitudinal cohort study2024 · 12 citations
  3. 3Trajectories of depressive symptoms and subjective well-being before and after the onset of the COVID-19 pandemic: Two six-year longitudinal studies2024 · 3 citations
  4. 4Mental health of individuals with pre-existing mental illnesses at the beginning of the COVID-19 pandemic: results of the German National Cohort (NAKO)2024 · 1 citations
  5. 5What factors contributed to mental well-being trajectories during the COVID-19 pandemic? A latent growth and multiple predictor analysis among German adults from 2015 to 20212025