Renal cell carcinoma associated with von Hippel–Lindau syndrome: an ambispective study

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Ambispective study shows 93.3% overall survival in 30 patients with RCC associated with VHL syndrome, indicating effective organ-sparing treatments.

Overall survival rate at four years reached 93.3% in patients with RCC associated with VHL syndrome, a positive outcome for treatment strategies.
Among 28 patients with non-metastatic RCC, 74.2% achieved metastasis-free survival over a four-year follow-up period.
Radical surgery for primary non-metastatic RCC yielded an 88.9% overall survival and disease-specific survival at four years.
Patients diagnosed with distant metastases presented a reduced 66.7% overall survival at the four-year mark, emphasizing treatment challenges.

Волкова et al. (2025) studied this question.

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View Full Paper

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Authors

Ambispective study shows 93.3% overall survival in 30 patients with RCC associated with VHL syndrome, indicating effective organ-sparing treatments.

Overall survival rate at four years reached 93.3% in patients with RCC associated with VHL syndrome, a positive outcome for treatment strategies.
Among 28 patients with non-metastatic RCC, 74.2% achieved metastasis-free survival over a four-year follow-up period.
Radical surgery for primary non-metastatic RCC yielded an 88.9% overall survival and disease-specific survival at four years.
Patients diagnosed with distant metastases presented a reduced 66.7% overall survival at the four-year mark, emphasizing treatment challenges.

Волкова et al. (2025) studied this question.

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