Key result
Nephron sparing surgery for renal cell carcinoma in von Hippel-Lindau disease resulted in 5- and 10-year cancer-specific survival rates of 100% and 81%, respectively.
Why the study?
Does surgery (radical nephrectomy or nephron sparing surgery) improve survival in patients with renal cell carcinoma and von Hippel-Lindau disease?
Cohort (n=65)
Yes
Does surgery (radical nephrectomy or nephron sparing surgery) improve survival in patients with renal cell carcinoma and von Hippel-Lindau disease?
Nephron sparing surgery provides effective initial treatment for renal cell carcinoma in von Hippel-Lindau disease, yielding high 5-year survival despite high rates of eventual local recurrence.
No takes yet. Share an insight, caveat, or question.
May inform surgical decisions for VHL-associated RCC; leaves open need for prospective trials on technique and surveillance.
Steinbach et al. (1995) conducted a cohort in Renal cell carcinoma in von Hippel-Lindau disease (n=65). Nephron sparing surgery vs. Radical nephrectomy was evaluated on 5-year cancer-specific survival rate. Nephron sparing surgery for renal cell carcinoma in von Hippel-Lindau disease resulted in 5- and 10-year cancer-specific survival rates of 100% and 81%, respectively.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: