Molecular Characterization of Newcastle Disease Virus Isolates from Live Bird Markets and Commercial Farms in Zaria, Nigeria, based on Partial Fusion Genee

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Discussion

Molecular analysis identifies virulent Newcastle Disease Virus strains in chickens, suggesting vaccine efficacy issues.

All ten NDV isolates were confirmed to be virulent, indicating potential vaccine failure risks.
Phylogenetic analysis revealed significant divergence of over 20% from common vaccine strains like La Sota and Komarov.
Molecular techniques like RT-PCR were utilized to amplify and sequence the partial F gene of the isolates collected.
These findings underscore the need for further studies to explore vaccine efficacy against circulating NDV variants.

Hamisu et al. (2025) studied this question.

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View Full Paper

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Authors

Molecular analysis identifies virulent Newcastle Disease Virus strains in chickens, suggesting vaccine efficacy issues.

All ten NDV isolates were confirmed to be virulent, indicating potential vaccine failure risks.
Phylogenetic analysis revealed significant divergence of over 20% from common vaccine strains like La Sota and Komarov.
Molecular techniques like RT-PCR were utilized to amplify and sequence the partial F gene of the isolates collected.
These findings underscore the need for further studies to explore vaccine efficacy against circulating NDV variants.

Hamisu et al. (2025) studied this question.

View Full Paper

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Bookmark