August 11, 2025The Science of The Total EnvironmentOpen Access

Route-specific ecotoxicogenomic responses of the honey bee Apis mellifera to imidacloprid revealed by co-expression analysis

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Authors

ILIsabella Cristina de Castro LippiSouthern Cross University JAJuliana AfonsoBrazilian Agricultural Research Corporation JSJaine da Luz SchefferUniversidade Estadual Paulista (Unesp)

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Implication

Ecotoxicogenomic analysis shows distinct transcriptomic responses in honey bees exposed to imidacloprid, indicating route-specific effects on health and foraging behavior.

Key Points

Imidacloprid exposure triggered distinct transcriptomic changes in honey bees, affecting multiple biological pathways.
Two unique co-expression networks were identified for oral and contact exposure, comprising 263 and 249 genes, respectively.
Key hub genes were linked to essential processes such as immune regulation, cellular signaling, and energy metabolism.
Integration of transcriptomic analyses highlights the need for better pesticide regulations to protect pollinator health.

Cite This Study

Lippi et al. (2025) studied this question.

synapsesocial.com/papers/68a360e70a429f7973329736 https://doi.org/10.1016/j.scitotenv.2025.180228

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Implication

Ecotoxicogenomic analysis shows distinct transcriptomic responses in honey bees exposed to imidacloprid, indicating route-specific effects on health and foraging behavior.

Route-specific ecotoxicogenomic responses of the honey bee Apis mellifera to imidacloprid revealed by co-expression analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

Route-specific ecotoxicogenomic responses of the honey bee Apis mellifera to imidacloprid revealed by co-expression analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

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