Abstract Background As a major modifiable risk factor for cardiovascular diseases worldwide, hypertension novel biomarkers that integrate inflammatory and metabolic pathways may improve risk stratification. The association between the red cell distribution width-to-albumin ratio (RAR), a newly identified inflammatory biomarker, and hypertension has not been systematically evaluated in population-based studies. Methods A cross-sectional study included 7,878 adults. Weighted multivariable logistic regression and threshold effect models were employed to analyze nonlinear associations, with subgroup analyses exploring heterogeneity. Results RAR showed a linear positive association with hypertension (adjusted OR = 1.26 per unit, 95%CI:1.09–1.44, P 40 years. Conclusion This study confirmed a linear positive correlation between red blood cell distribution width and albumin ratio (RAR) and the prevalence of hypertension, RAR ≥ 3.4 was associated with higher hypertension prevalence and may help identify high-risk subgroups, particularly among diabetics, but its predictive value warrants validation through prospective cohort studies.
Zhao et al. (Sat,) studied this question.