Assessing participants’ experiences with the COVID-19 symptom diary in a clinical trial

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Daily symptom reporting revealed low energy was the most reported COVID-19 symptom at 88%.
Half of participants reported an unlisted symptom, with dizziness being the most common at 12%.
Qualitative interviews confirmed that all diary items were generally clear and easy to answer for participants.
Content validity of the COVID-19 symptom diary was supported, though some participants found global impression items vague.

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Qualitative interviews assessed content validity of the COVID-19 symptom diary in clinical trial participants, highlighting potential improvements.

Brown et al. (2025) studied this question.

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Qualitative interviews assessed content validity of the COVID-19 symptom diary in clinical trial participants, highlighting potential improvements.