Slowly Expanding Lesions in Pediatric-Onset Multiple Sclerosis

Valeria Pozzilli; Ferrán Prados; N.-Y. Kim; Omar Abdel‐Mannan; Riccardo Nistri; Philipp Goebl; Cheryl Hemingway; Asthik Biswas; Kshitij Mankad; Sniya Sudhakar; Amitav Parida; Sukhvir Wright; Evangeline Wassmer; Michael Eyre; Ming K. Lim; Thomas Rossor; Arman Eshaghi; Frederik Barkhof; Ermelinda De Meo; Olga Ciccarelli; Yael Hacohen

doi:10.1001/jamaneurol.2025.2619

Key Points

Slowly expanding lesions correlate with increased disability in pediatric-onset multiple sclerosis, and brain growth is a crucial factor.
Findings indicate that the presence of slowly expanding lesions is linked to disability progression in affected youth.
Cohort study analyzed data from younger individuals with pediatric-onset multiple sclerosis, revealing important associations.
This research highlights the role of brain growth in disability outcomes, emphasizing the need for early intervention.

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Implication

Cohort study examines disability progression in pediatric-onset multiple sclerosis, suggesting brain growth may be impacted.

Abstract

This cohort study examines the association between slowly expanding lesions and pediatric-onset multiple sclerosis among younger individuals, focusing on brain growth and disability progression.

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Cite This Study

Pozzilli et al. (2025) studied this question.

synapsesocial.com/papers/68a360f20a429f7973329b84 https://doi.org/10.1001/jamaneurol.2025.2619

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Slowly Expanding Lesions in Pediatric-Onset Multiple Sclerosis

Key Points

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Implication

Abstract

Discussion

Cite This Study

Slowly Expanding Lesions in Pediatric-Onset Multiple Sclerosis

Key Points

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Implication

Abstract

Discussion

Cite This Study

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