Histological and Immunohistochemical Findings of an Extremely Rare Multi‐Organ Metastasis of Fibrosarcoma in a Holstein Cow

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Case report details rare multi‐organ metastasis of fibrosarcoma, highlighting key histopathological and immunohistochemical findings.

Multi‐organ metastasis of fibrosarcoma was identified in a 4-year-old Holstein cow, presenting a rarely documented case.
Tissue analysis revealed spindle-shaped cells and positive immunoreactivity for vimentin, crucial for diagnosis.
The case involved systematic meat inspection revealing yellowish-white masses in vital organs like the liver and lungs.
This report calls for increased awareness of fibrosarcoma in cows, highlighting its potential for unusual presentations.

Namjou et al. (2025) studied this question.

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