Eculizumab as rescue therapy in refractory anti-NXP2 dermatomyositis with digestive vasculitis and gastrointestinal perforation: report of two cases

Journal Article Accepted manuscript Eculizumab as rescue therapy in refractory anti-NXP2 dermatomyositis with digestive vasculitis and gastrointestinal perforation: report of two cases Get access Loraine Combemale , Loraine Combemale Department of Dermatology, Referral Center for Autoimmune Blistering Diseases, Hôpital Avicenne, Assistance Publique—Hôpitaux de Paris, Sorbonne Paris Nord University, Bobigny, France Corresponding authors: Loraine Combemale, 125 rue de Stalingrad, 93000 Bobigny, France, [email protected] Search for other works by this author on: Oxford Academic PubMed Google Scholar Alexandre-Raphael Wery , Alexandre-Raphael Wery Department of Internal Medicine and Clinical Immunology, Referral Center for inflammatory myopathies, Research Center in myology UMR974, Hôpital La Pitié-Salpêtrière, Assistance Publique—Hôpitaux de Paris, Sorbonne University, Paris, France Search for other works by this author on: Oxford Academic PubMed Google Scholar Gérôme Bohelay , Gérôme Bohelay Department of Dermatology, Referral Center for Autoimmune Blistering Diseases, Hôpital Avicenne, Assistance Publique—Hôpitaux de Paris, Sorbonne Paris Nord University, Bobigny, France Search for other works by this author on: Oxford Academic PubMed Google Scholar Mehdi Zerrari , Mehdi Zerrari Department of Dermatology, Referral Center for Autoimmune Blistering Diseases, Hôpital Avicenne, Assistance Publique—Hôpitaux de Paris, Sorbonne Paris Nord University, Bobigny, France Search for other works by this author on: Oxford Academic PubMed Google Scholar Julien Culerrier , Julien Culerrier Department of Internal Medicine, Hôpital Avicenne, Assistance Publique—Hôpitaux de Paris, Bobigny, France Search for other works by this author on: Oxford Academic PubMed Google Scholar Robin Dhote , Robin Dhote Department of Internal Medicine, Hôpital Avicenne, Assistance Publique—Hôpitaux de Paris, Bobigny, France Search for other works by this author on: Oxford Academic PubMed Google Scholar Anissa Martins-Bexiga , Anissa Martins-Bexiga Department of Medical-Surgical Intensive Care Unit, Hôpital Avicenne, Assistance Publique—Hôpitaux de Paris, Bobigny, France Search for other works by this author on: Oxford Academic PubMed Google Scholar Armelle Bardier , Armelle Bardier Department of Pathology, Hôpital La Pitié-Salpêtrière, Assistance Publique—Hôpitaux de Paris, Sorbonne University, Paris, France Search for other works by this author on: Oxford Academic PubMed Google Scholar Antoine Diep , Antoine Diep Laboratory of Immunology, Hôpital Saint-Louis, Assistance Publique—Hôpitaux de Paris, Paris, France Search for other works by this author on: Oxford Academic PubMed Google Scholar Yves Allenbach , Yves Allenbach Department of Internal Medicine and Clinical Immunology, Referral Center for inflammatory myopathies, Research Center in myology UMR974, Hôpital La Pitié-Salpêtrière, Assistance Publique—Hôpitaux de Paris, Sorbonne University, Paris, France Search for other works by this author on: Oxford Academic PubMed Google Scholar ... Show more Frédéric Caux , Frédéric Caux Department of Dermatology, Referral Center for Autoimmune Blistering Diseases, Hôpital Avicenne, Assistance Publique—Hôpitaux de Paris, Sorbonne Paris Nord University, Bobigny, France Search for other works by this author on: Oxford Academic PubMed Google Scholar Olivier Benveniste Olivier Benveniste Department of Internal Medicine and Clinical Immunology, Referral Center for inflammatory myopathies, Research Center in myology UMR974, Hôpital La Pitié-Salpêtrière, Assistance Publique—Hôpitaux de Paris, Sorbonne University, Paris, France Search for other works by this author on: Oxford Academic PubMed Google Scholar Rheumatology, keaf431, https://doi.org/10.1093/rheumatology/keaf431 Published: 08 August 2025 Article history Received: 26 May 2025 Revision received: 02 July 2025 Accepted: 20 July 2025 Published: 08 August 2025