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August 13, 2025MycobiologyOpen Access

Impact of Clove Oil on Biofilm Formation in Candida albicans and Its Effects on Mice with Candida Vaginitis

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Authors

YGYuan GaoTianjin University of Traditional Chinese MedicineZWZhuo WangUniversity of Shanghai for Science and TechnologyXWXin WangHarbin University of Commerce

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Implication

Observational analysis shows clove oil reduces biofilm formation in Candida albicans, suggesting therapeutic potential in vaginitis.

Key Points

  • Clove oil inhibits biofilm maturation of Candida albicans, reducing its pathogenic ability and symptoms of vaginitis.
  • The study measured the therapeutic effects using the ICR mouse model and identified pathways through network pharmacology.
  • Evaluation involved methods such as qPCR to assess gene levels and Western blot for protein analysis of key targets.
  • These findings highlight clove oil's potential to offer a natural remedy for managing Candida-related infections.

Cite This Study

Gao et al. (2025) studied this question.

synapsesocial.com/papers/68a363490a429f797332a094https://doi.org/10.1080/12298093.2025.2537477
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