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August 13, 2025Scientific ReportsOpen Access

Genetic diversity analysis of IVM resistant Haemonchus contortus in sheep in inner Mongolia of China

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Authors

YZYanmin ZhangChina Pharmaceutical UniversityHWHaifeng WenInstitute of Grassland ResearchHZHao ZhangNanjing University of Science and Technology

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Implication

Analysis reveals genetic diversity and resistance in Haemonchus contortus in sheep, suggesting regional treatment impacts.

Key Points

  • Genetic diversity and resistance levels in Haemonchus contortus were characterized, showing specific haplotypes related to IVM treatment.
  • The study identified 13 haplotypes among the IVM-resistant samples, with high nucleotide diversity at 0.00623 and haplotype diversity at 0.926.
  • Phylogenetic analysis linked IVM-RR strains closely with certain populations in China and Pakistan, indicating low genetic differentiation.
  • The findings suggest regional treatment practices may influence the genetic structure of the parasite, warranting further research into resistance management.

Cite This Study

Zhang et al. (2025) studied this question.

synapsesocial.com/papers/68a363490a429f797332a192https://doi.org/10.1038/s41598-025-14909-w
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  5. 5Genetic diversity and population structure of <i>Haemonchus contortus</i> isolates from sheep across Xinjiang, China2025