Patient-Reported Outcome Measures Poorly Correlate with Objective Inflammatory Bowel Disease Activity Measures: A Systematic Review

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Discussion

Systematic review shows PROMs have weak correlations with IBD activity measures, indicating limitations in their use.

Weak positive correlations were found between patient-reported outcome measures and endoscopic scores in Crohn's disease.
Nineteen studies were included, indicating variability in how PROMs relate to clinical measures across IBD.
The analysis highlighted limited concordance between PROMs and laboratory measures like faecal calprotectin and C-reactive protein.
Future research aims to refine PROMs and develop composite indices to enhance their reliability and relevance.

Calvet et al. (2025) studied this question.

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