Metastasis of Breast Cancer in Myometrium, Detected Exclusively Through 18F-FDG PET/CT

Yeong-Shin Hsiao; Shu-Chane Shen; Shih‐Chuan Hsiao

doi:10.1097/rlu.0000000000006055

July 23, 2025Clinical Nuclear Medicine

Metastasis of Breast Cancer in Myometrium, Detected Exclusively Through 18F-FDG PET/CT

View at Publisher

Ask AI

Bookmark

Share

Key Points

Myometrial metastasis was confirmed in a breast cancer patient, indicating a need for careful imaging interpretation.
The lesion identified had a high SUV in 18F-FDG PET/CT, which is critical for accurate diagnosis.
Hysterectomy and bilateral oophorectomy confirmed the presence of metastatic mammary carcinoma in this case.
Traditional imaging may misinterpret malignant lesions, highlighting the importance of advanced diagnostic techniques.],
simple_explanation':'Breast cancer can spread to other parts of the body, like the myometrium, which is the middle layer of the uterus. In one case, a woman discovered a tumor through a special scan called 18F-FDG PET/CT after years of treatment. This scan helped show that her breast cancer had spread there, proving it’s essential for catching such cancers early. This means doctors need to be careful about diagnosing tumors in the uterus to avoid missing potential cancers. 🩺'} }
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
} ,
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}
}

Ask about this paper

Answers are grounded in this paper and cite their sources.

Implication

Case report highlights early detection of myometrial metastasis in a breast cancer patient, suggesting PET/CT's crucial role in diagnosis.

Abstract

We share the case of a 50-year-old woman with isolated myometrial metastasis of recurrent invasive breast ductal carcinoma. Eight years after initial diagnosis at stage IIIC, a hypodense myometrial tumor was spotted in whole-body CT, which was also noted as a lesion with high SUV in 18 F-FDG PET/CT. Myometrial metastatic mammary carcinoma was then pathologically proven after hysterectomy and bilateral oophorectomy. This case warns us to be alert to how easily malignant uterine lesions could be misjudged as benign in traditional imaging and, consequently, how irreplaceable PET/CT is in the early diagnosis and treatment of malignant diseases.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Hsiao et al. (2025) studied this question.

synapsesocial.com/papers/68a363670a429f797332a9d1 https://doi.org/10.1097/rlu.0000000000006055

View at Publisher

Ask AI

Bookmark

Share

Metastasis of Breast Cancer in Myometrium, Detected Exclusively Through 18F-FDG PET/CT

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Metastasis of Breast Cancer in Myometrium, Detected Exclusively Through 18F-FDG PET/CT

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Keep reading

Keep reading