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August 15, 2025Animal BioscienceOpen Access

Protection of bovine mammary epithelial cells against lipopolysaccharide-induced inflammatory responses using Centella asiatica through its antioxidant and anti-inflammatory activities

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Authors

DKDo Hyun KimHKHyuk-Cheol KwonJHJong-Hyun Han

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Overview

In vitro analysis shows Centella asiatica reduces inflammation in bovine mammary cells, suggesting it may aid mastitis prevention.

Key Points

  • Centella asiatica extract significantly attenuates lipopolysaccharide-induced inflammation in bovine mammary epithelial cells, enhancing lactation functions.
  • CE60, the most effective extract, reduces pro-inflammatory cytokines and lowers oxidative stress in bovine cells exposed to LPS.
  • This observational analysis implicates Centella asiatica as a natural remedy against mastitis in dairy cattle, offering economic benefits.
  • Findings suggest further exploration of CE60 could enhance disease management strategies in the dairy industry.

Cite This Study

Kim et al. (2025) studied this question.

synapsesocial.com/papers/68a365560a429f797332b11ehttps://doi.org/10.5713/ab.25.0089
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