Flow-driven translocation of comb-like copolymer vesicles through a nanochannel: the influence of nanochannel size and vesicle membrane thickness

Minmin Zhou; Qiaoyue Chen; Danfeng Liu; Lili Zhang; Mingming Ding

doi:10.1039/d5sm00560d

January 1, 2025Soft Matter

Flow-driven translocation of comb-like copolymer vesicles through a nanochannel: the influence of nanochannel size and vesicle membrane thickness

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Key Points

Translocation rates of vesicles are affected by both nanochannel size and membrane thickness, emphasizing their importance in material design.
Key evidence shows that varying nanochannel dimensions and membrane characteristics significantly alters macromolecule movement in confined spaces.
Analysis combines lattice-Boltzmann method for fluid dynamics with molecular dynamics for polymers, creating a robust simulation framework.
Findings highlight the complex interactions in vesicle translocation, suggesting design considerations for nanofluidic applications.

Implication

Hybrid simulation reveals the influence of nanochannel size and vesicle thickness on translocation rates.

Abstract

We employed a hybrid simulation approach that combines a lattice-Boltzmann (LB) method for simulating fluid flow with a molecular dynamics (MD) model for the polymers to investigate the translocation of...

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Cite This Study

Zhou et al. (2025) studied this question.

synapsesocial.com/papers/68a365600a429f797332b5e6 https://doi.org/10.1039/d5sm00560d

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Flow-driven translocation of comb-like copolymer vesicles through a nanochannel: the influence of nanochannel size and vesicle membrane thickness

Key Points

Implication

Abstract

Discussion

Cite This Study

Flow-driven translocation of comb-like copolymer vesicles through a nanochannel: the influence of nanochannel size and vesicle membrane thickness

Key Points

Implication

Abstract

Discussion

Cite This Study

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