This model reveals a link between axial elongation and orbital fat in myopia, suggesting new treatment paths.
Current myopia models cannot explain important clinical findings such as unilateral progression, adult onset, and optic disc tilt. We hypothesize that chronic downgaze induces mechanical traction via the superior oblique muscle, leading to orbital fat redistribution and axial elongation. This model redefines myopia as a potentially reversible mechanical disease. This hypothesis is testable through longitudinal MRI and ultrasound imaging and may lead to novel treatment strategies.
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Masaru Numagaki (2025) studied this question.
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